Behind the Science - Season 7

One part of an infection preventionists’ duties is to make sure that the health care workers are following their facilities’ hand hygiene protocols. Yet, no matter the tools or tricks that have been offered and created by investigators and inventors, health care professionals still do not follow the hand hygiene guidelines 100% of the time. So Behind the Science asked health care workers off the record why they find themselves not following strict hand hygiene protocol to get an insight on the reasons.

There has been a great push to destigmatize conditions like depression and anxiety in recent years. And while great progress has been made in this regard, stigma remains for other psychiatric conditions, like bipolar disorder, schizophrenia, and borderline personality disorder. During the 2022 Annual Psychiatric Times™ World CME Conference in San Diego from August 11-13, several doctors spoke on this topic. Dr. Culpepper spoke about bipolar disorder and borderline personality disorder, Dr. Schneck spoke about psychiatry in general, Dr. Clayton spoke about postpartum depression, and Dr. Rao spoke about schizophrenia.

Recently, US News and World Report released its annual rankings on “Best Hospitals for Cancer,” in which 913 hospitals are evaluated and the top 50 ranked. Among the top centers were the Hospitals of the University of Pennsylvania and the Siteman Cancer Center at Barnes-Jewish Hospital. Following the report, CancerNetwork® editors sat down with Robert H. Vonderheide, MD, DPhil, director of the Abramson Cancer Center at the University of Pennsylvania in Philadelphia, and Timothy Eberlein, MD, director of the Alvin J. Siteman Cancer Center in Saint Louis, Missouri, about what this honor means to them and what makes their centers stand out from the rest.

Findings of a recent JAMA study exploring compared incidence of COVID-19 in vaccinated NBA players and staff showed that those who received a booster dose were significantly less likely to be infected during the Omicron wave. On this week’s Behind the Science, study authors Christina Mack, PhD, MPH, and Caroline Tai, PhD, MPH, who together lead epidemiologic efforts for agile analytics at IQVIA, discuss the preventive implications of the findings and how scientific and operational real-world data such as these can be leveraged as a foundation for future public health and clinical applications at scale.

A panel of experts discuss allergic rhinitis and important counseling points and tactics. They review the current standard of care and identify specific treatment considerations for children, women, elderly, and others.

Nina Kotter, MD, the Associate Chief Medical Officer of Clinical AI for Radiology Partners, Sonia Gupta, MD, the Chief Medical Officer for Change Healthcare, and Morris Panner, the President of Intelerad Medical Systems, discussed challenges with radiology workflows and how artificial intelligence (AI) could improve workflow efficiencies and possibly facilitate improved patient outcomes down the line.

While onsite at the American Headache Society’s Annual Scientific Meeting, NeurologyLive caught up with a number of experts in the care and science of headache medicine to hear about some of the hottest topics in the clinical care of migraine. They offered insights into the state of science around status migrainosus, the disparity in funding relative to disease burden, the underlying cellular process in migraine, and the research into psychedelics as therapeutics for headache disorders.

In the first year of the COVID-19 pandemic, clinicians were overwhelmed and challenged caring for patients with severe COVID-19. These patients spent more time in hospitals and hooked up to catheters and ventilators in the ICUs and CCUs, thus exposing them to more health care associated infections. Listen in on clinicians’ experiences and insights into antimicrobial prescribing practices in the midst of the early, anxiety-ridden days of the pandemic.

Amid the COVID-19 pandemic and beyond, rheumatologists have felt the effects of physician burnout in part due to a shortage of rheumatologists, keeping up with changes in telemedicine, and general COVID-related fatigue. How did these rheumatologists prevent burnout during this time?

Findings of a recent Oliver Wyman study commissioned by IntelyCare revealed that lower occupancy rates due to nurse staffing shortages are estimated to cause nearly $20 billion in unrealized revenue for the post-acute care industry. On this week’s Behind the Science, The American Journal of Managed Care® spoke with several stakeholders involved in the analysis to discuss the industry implications of these findings, how use of contingent nursing labor may provide a cost-effective solution, and what health care systems should be aware of amid a looming recession.

Immunotherapy has drastically improved outcomes for patients with advanced skin cancers, but more work still needs to be done in this field. Two experts, Jedd D. Wolchok, MD, PhD, FASCO, and Barbara T. Ma, MD, MS, discuss the impact immunotherapy has had on different types of skin cancer, including melanoma and basal cell and squamous cell carcinoma, as well as the potential side effects of these drugs, and where research should turn to next.

CGTLive sat down with experts to learn more about manufacturing challenges in the cell therapy space and strategies being pursued to address these challenges at the 2022 Onco Cell Therapy Summit. Conversations included Dr. Serena De Vita’s experience with Novartis’ T-Charge platform designed to expedite manufacturing; Dr. Philip Lee’s work with Senti Biosciences to streamline manufacturing; Dr. Michael Leek’s perspective on lessons learned with cell therapy manufacturing throughout the years; and Raphaël Ognar on the advantages of partnering for ease of manufacturing.