Deep Dive - Season 8

Veterinary technician Kirsten Oliver outlines the new wearable technology for pets available on the market just in time for gifting this holiday season. She describes their benefits and drawbacks, the array of features these wearable techs have, and more.

The FDA approved RBX2660 for the prevention of recurrent CDI last week, making it the first ever approved live microbiota therapeutic. Dr. Sahil Khanna was an investigator on the PUNCH CD3 study testing the product and spoke about the excitement of the drug and why it might result in a significant reduction in C difficile cases in the coming years.

Dr. Patricia Piers, head of R&D, Ophthalmic Implants at Johnson & Johnson Surgical Vision, recently received the 2022 Women in Ophthalmology Scientific Contribution Award. This award recognizes a physician or non-physician scientist who has made significant contribution in the field of ophthalmology.

In an interview with Pharmacy Times, allergist Maxcie Sikora, MD, discussed steps parents and clinicians can take to minimize the risk of food-induced allergic reactions during the holiday season. Parties and get-togethers often present challenges, with home-cooked food that can have hidden allergens. To avoid allergic reactions, Sikora suggested some steps families can take, including hosting events and teaching children to ask before eating.

Dr. Elizabeth Sapey provides an in-depth look at the World Health Organization’s recent decision to recommend the use of remdesivir in patients with severe COVID-19, including results from the PINETREE study that were the “linchpin” for the change and how she uses remdesivir in her own clinical practice.

Hanan Goldberg, MD, MSc, shares notable findings from the study, “Disparities regarding shared decision making in prostate cancer screening,” which was presented at the 74th annual meeting of the Northeastern Section of the American Urological Association. Goldberg is an assistant professor at SUNY Upstate Medical University in Syracuse, New York.

Multinational consumer goods company Unilever announced a voluntary product recall of various popular dry shampoo aerosol products—including those from brands such as Dove, Nexxus, Suave, TIGI and TRESemmé—due to risk of increased benzene levels, in mid-October. The announced recall, per the FDA, coincided with an internal investigation by the company into the cause of increased benzene exposure risk—identifying the products’ aerosol propellant, provided by an outside supplier, as the source. As the FDA noted, benzene is a human carcinogen that, through increased inhaled, oral or subcutaneous exposure, may increase risk of leukemia and other blood cancers or disorders. While benzene is prevalent in daily indoor and outdoor environments, recalled products generally carry a substantial risk of increased exposure, and the FDA recommends affected consumers stop using recalled products and report adverse reactions to their adverse event reporting program.

As T-cell redirection therapies such as CAR T-cell therapies and bispecific antibodies become more common in the clinical setting, questions remain on how these therapies can be combined and sequenced. Samir Parekh, MD, and colleagues from the Tisch Cancer Institute conducted research on the efficacy of T-cell redirection therapies used sequentially to treat patients with relapsed/refractory multiple myeloma. CGTLive sat down with Parekh to learn more about the study’s findings.

On this episode of Deep Dive, retina specialist Gareth Lema, MD, PhD, explains the importance of recognizing the signs and symptoms of eye stroke and timely treatment for patients. He also discusses the role of optical coherence tomography and a novel eye stroke program at Mount Sinai Health System that involves collaboration among ophthalmologists, the stroke service, and emergency department physicians.

Dr. Giselle Mosnaim discusses a recent study that she worked on. The study looked at the effectiveness of a digital inhaler system in improving adherence and technique to lead to better outcomes in patients with asthma.

Alison Cowan, MD, board-certified ob-gyn and head of medical affairs for Mirvie, discusses the latest predictions for women’s health in 2023. From Maternal mortality to preterm birth, Cowan dives into what health conditions will be affecting women most in 2023 and how the specialty is trying to combat these issues.

As treatments for multiple myeloma continue to improve, clinicians must still face a scary reality for their patients: immune deficiency. Researchers and doctors alike are still trying to get a better understanding of which patients are more likely to have severe immune issues, which could lead to life-threatening infections. In this episode of Deep Dive, we’ll hear from Dr. Joshua Richter from the Tisch Cancer Institute at Mount Sinai, about his research in patients with myeloma who have a high burden of infection, and why patient-provider communication is essential in this setting.

The rising health care spend is a significant issue facing employers who are accountable for the health care coverage of over 180 million Americans. On today's Deep Dive, Neil Goldfarb, president and CEO of the Greater Philadelphia Business Coalition on Health (GPBCH), discussed the utility of business coalitions in driving transparency for value-based health care, the accomplishments and persistent challenges GPBCH has had so far, and the future impact of these coalitions as health care delivery continues to evolve.

Sheriff Ibrahim, MD,PhD, provides key pearls from his co-directed session as the 2022 Annual ASDS Meeting, “Defining ‘High-Risk’ for Squamous Cell Carcinoma: Implications for Treatment Paradigms.” Ibrahim is the founder of Rochester Dermatologic Surgery and an associate professor of dermatology at the University of Rochester Medical Center in Rochester, New York.

Calvin Ke, MD, PhD, provides further perspective into a study he led examining trends in the association between diabetes and cardiovascular events from 1994 through 2019. Results of the study, which were published in JAMA, provide insight into contemporary trends in cardiovascular risk among people with diabetes as well as the overall impact diabetes on prognosis in the general population.

Didier Pittet, MD, MS, CBE, a renowned epidemiologist and credited with revolutionizing patient care processes in hospitals by replacing hand washing with soap and water with the systematic use of alcohol-based handrubs, joins Deep Dive to discuss the Clean Hospitals Day Initiative to discuss the biggest challenges that environmental hygiene personnel face and what can be done about them.

CancerNetwork’s Ariana Pelosci spoke with Odion Binitie MD, an orthopedic surgeon at Moffitt Cancer Institute, about the mentorship program which connects medical professionals with medical students. This is part of the Faculty Diversity in Oncology program at Moffitt which partnered with the Brain Expansions Scholastic Training program that helps to connect underrepresented or disadvantaged youth to healthcare professionals.

One of the recurring challenges in the medical cannabis space is the difficulty in conducting research because of the plant’s Schedule I status. Although there are some researchers diving in with special licenses to conduct clinical studies, there are others that are looking at real-world users to supply data. For instance, Dr. Daniel J. Kruger is a Research Investigator with the Population Study Center at the University of Michigan and Principal Investigator on a study being conducted with the Releaf app. Here, Dr. Kruger shares his interest and background in these types of surveys and his plans for the current study with Releaf on chronic pain.

Dr. Renee Schmid from the Pet Poison Helpline joins to educate listeners on the risk’s pets face with the sweets we get for Halloween, what kind of costumes work best for pets, and what to do if you suspect your pet has ingested something that is more trick and less treat.

In a wide-ranging video interview, Wendie Berg, MD, discussed her family history with breast cancer, the founding of www.DenseBreast-info.org, emerging research with contrast-enhanced mammography and the need for a national standard on breast density notifications.

This interview, with Carina Dolan, PharmD, Editor in Chief of Pharmacy Market Outlook, discusses the latest Pharmacy Market Outlook report that was released, and it highlights the big picture moving forward for pharmacists in hospitals and health systems.