Deep Dive - Season 9

Michael Levy, MD, PhD talked about the differences between 2 similar diseases, multiple sclerosis and neuromyelitis optica spectrum disorder. He spoke about the differences in how clinicians perceived disease biology and their comprehension of the disease currently. Additionally, Levy discussed the biomarker that is tested for the diagnosis of NMOSD in comparison with multiple sclerosis.

Luke Gormley, PharmD, BCPS, a clinical pharmacy specialist at Allegheny General Hospital, discussed how pharmacists are involved in the management of inclisiran, a small interfering RNA treatment to manage low-density lipoprotein cholesterol (LDL-C). In addition to managing the treatment itself and educating patients, Gormley noted that pharmacists play a crucial role in implementing the treatment and establishing payment models.

Despite vaccines and other preventative tools, many people are still at risk for severe or fatal COVID-19 infection. Simon Portsmouth, MD, FRCP, delves into Shionogi’s Ensitrelvir (S-217622), a COVID-19 antiviral with the potential to remain effective against the new and highly infectious Omicron subvariants.

Megan H Noe, MD, MPH, Assistant Professor of Dermatology at Harvard Medical School, discussed the brief history of her and her colleagues’ role in the ongoing pandemic, including that of as facilitators of treatment and vaccine information. She also reviewed ongoing plans to further strengthen the dermatology blueprint in future pandemics and outbreaks—regardless of how they impact the skin.

In honor of Endometriosis Awareness Month in March, Rachael Cullifer, MD, sat down to discuss the most common misconceptions about the disease, clinical pearls for diagnosis and management, and the importance of listening to your patients, especially when it comes to endometriosis.

Gregory Day, MD, MSc, MSCI, FAAN, is the lead investigator in the ExTINGUISH trial, a neurologist at Mayo Clinic in Jacksonville Florida and is also a behavioral neurologist by training with an additional focus in a typical presentation to dementia and including patients with memory and thinking problems after autoimmune encephalitis or that present inflammatory causes of dementia and cognitive impairment.

CancerNetwork® spoke with Andrea C. Enzinger, MD, an assistant professor of medicine at Harvard Medical School and a physician at Dana-Farber Cancer Institute, about a recent study that aimed to determine the prevalence of racial and ethnic disparities in end-of-life opioid access among Black, Hispanic, and White patients with cancer. After reviewing the study results—which highlighted a substantial gap in access among Black and Hispanic patients—Enzinger discussed how a potential multi-pronged strategy may work to mitigate these disparities including bias training for physicians and logistical support for patients.

Dr. Christina Carter recently sat down with Dental Products Report to discuss the strong link between the state of the economy and children’s oral health. With prices rising, parents may not have the option of regular dentist visits, leading to potential problems with their children’s oral health in the future. Dr. Carter discusses ways to mitigate these potential problems as we head into a potential downturn in the economy.

A lot of information is up in the air when it comes to traveling with pets on planes. That’s why on this episode of “Deep Dive”, a veterinarian at Delta Air Lines answers frequently asked questions pet owners may have on this topic—from the difference between traveling with dogs versus cats to the required documentation forms—so you can inform clients on what to know before their next trip.

Reanne Booker, MN, NP, nurse practitioner with the palliative and end of life care services program at the Foothills Medical Centre at Alberta Health Services in Calgary, Alberta, as well as a PhD candidate at the University of Victoria in British Columbia, shares how nurses can increase patient understanding on the role of palliative care in oncology.

The contraceptive landscape is ever changing. From new long-acting reversible contraception to nonhormonal options, pharmaceutical companies and researchers alike are continuously coming up with new forms of contraception to provide every woman with not only the ability to prevent pregnancy, but also treat other non-pregnancy related symptoms such as acne and heavy periods. In this interview, Michael Krychman, MD, a community-based gynecologist in Newport Beach, California, takes a look at 2022 advances within the contraceptive space, as well as looks toward the future.

Colleen A. Kraft, MD, senior medical director of clinical adoption at Cognoa, discusses the value of early autism spectrum disorder (ASD) identification in children. Kraft details the difficulties young children with ASD face because of not understanding social cues, but how treatment is now available to help these children. Early diagnosis and treatment can help reduce symptoms as early as kindergarten, and children with ASD can find success and thrive.

Initially starting in 2011 as a ministry that offered food, clothing, and other services to community members in Pittsburgh, the Neighborhood Resilience Project has since gained national attention for its work on promoting health and resiliency in trauma-affected communities. Reverend Paul Abernathy, CEO of the Neighborhood Resilience Project, speaks on the challenges presented in managing underserved communities and advice he would give to other community stakeholders in pursuing health equity.

Winter months can wreak havoc on skin. The dryness related to dry, outdoor air and indoor heating, can rob skin of its natural moisture. Symptoms of eczema and atopic dermatitis can be exasperated this time of year. Doctor Bernard Cohen, professor of pediatrics and dermatology at John Hopkins University School of Medicine in Baltimore talks to Dermatology Times senior editor, Carrie Nagorka, about how parents can help relieve some of those winter flare-ups in children.

On this episode of Deep Dive, Dr. David S. Boyer joins us to discuss 48-week results from the PHOTON study detailing the safety and efficacy of high-dose aflibercept in the treatment of diabetic macular edema. Boyer is an adjunct professor of ophthalmology at the University of Southern California’s Keck School of Medicine and a partner in Retina Vitreous Associates Medical Group in Los Angeles.

Rebekah Martin, senior VP of reward, inclusion, and talent acquisition at AstraZeneca, discusses recruiting talent in pharma, including finding and keeping the right talent, identifying and nurturing talent (students, specifically), and diversity in the workforce.

The US Food and Drug Administration recently approved ibrexafungerp (Brexafemme; Scynexis) for the reduction in the incidence of recurrent vulvovaginal candidiasis (RVVC), otherwise known as chronic yeast infections. Now, ibrexafungerp is approved for the treatment of both vulvovaginal candidiasis and the reduction in the incidence of RVVC. Marco Taglietti, MD, president and CEO of Scynexis, sits down with Contemporary OB/GYN® to discuss this recent approval and what it means for the chronic yeast infection landscape.

Respiratory syncytial virus (RSV) is a common respiratory virus that typically causes mild, cold-like symptoms. However, this season we’ve seen an unprecedented number of severe RSV cases in young children and older adults. Dr. Tina Tan joins Deep Dive to explain why this year’s RSV is so early and deadly, as well as to discuss the most promising candidates in the race to the first-ever RSV vaccine.

Phillip S. Low, PhD, discusses the recent approval of pafolacianine for patients with lung cancer. Low, the pioneer behind this imaging agent talked about how this can be of great importance for patients in this population. Additionally, he reviewed how doctors can begin to implement this into practice to best help find and detect cancerous lesions.

Lisa Hunter Romanelli, PhD, discusses steps made to combat the mental health crisis declared over 1 year ago by the American Academy of Pediatrics. This discussion includes how COVID-19 exasperated mental health issues in children, but a mental health crisis was already present before the start of the pandemic. While more needs to be done, individual providers can support children by learning how to diagnose and treat mental health issues.

According to the World Wildlife Fund, Inc, nearly all species of sea turtles are classified as endangered, with 3 of the 7 existing species being critically endangered. On this episode of “Deep Dive,” Liz Barton, MA, VetMB, MRCVS, MCIPR, head of communications of VetCT, highlights VetCT initiatives aimed at supporting sea turtle research and welfare, including the company’s offering of free teleradiology reports and specialist advice to those treating and rehabilitating sick and injured sea turtles.

One of the recurring challenges in the medical cannabis space is the access for patients—from affordability to medical advice on what to use, patients need help. Veterans also have a unique challenge regarding access to medical cannabis if they have medical coverage through the VA. Veteran Cherissa Jackson of WE DECODE LLC sheds some light on these issues, hopes for the future, and her role as the medical cannabis program chair at the Cannabis Science Conference series this year.

Fibromyalgia, long COVID, and chronic fatigue syndrome have many of the same symptoms, so how do they differ? Where do they come from? And how are they differentiated? Infection Control Today® spoke with Seth Lederman, MD, a rheumatologist to answer questions about these 3 conditions.