Clinical

Calvin Ke, MD, PhD, provides further perspective into a study he led examining trends in the association between diabetes and cardiovascular events from 1994 through 2019. Results of the study, which were published in JAMA, provide insight into contemporary trends in cardiovascular risk among people with diabetes as well as the overall impact diabetes on prognosis in the general population.

Targeted therapies — that is, those that target specific biomarkers found on cancer cells — and immunotherapies have brought landmark change to the lung cancer space in recent years. Now patients are living longer, and often with a better quality of life, than those before them who had few treatment options beyond surgery and chemotherapy. In today’s episode of Behind the Science, hear from three experts in the space about how more personalized treatments are shaking up the lung cancer field.

Didier Pittet, MD, MS, CBE, a renowned epidemiologist and credited with revolutionizing patient care processes in hospitals by replacing hand washing with soap and water with the systematic use of alcohol-based handrubs, joins Deep Dive to discuss the Clean Hospitals Day Initiative to discuss the biggest challenges that environmental hygiene personnel face and what can be done about them.

The Heart Failure Society of America (HFSA) annual scientific meeting is a showcase for the latest advances in the management of heart failure. As part of their onsite coverage of the meeting, Practical Cardiology asked interview guests what they thought might stand out as the theme or biggest news from HFSA 2022 when looking back at the meeting in the future.

CancerNetwork’s Ariana Pelosci spoke with Odion Binitie MD, an orthopedic surgeon at Moffitt Cancer Institute, about the mentorship program which connects medical professionals with medical students. This is part of the Faculty Diversity in Oncology program at Moffitt which partnered with the Brain Expansions Scholastic Training program that helps to connect underrepresented or disadvantaged youth to healthcare professionals.

At the American Academy of Ophthalmology 2022 Meeting in Chicago, five experts discuss the biggest news in ophthalmology and what may be considered the defining topic of 2022. The topics discussed include advancements in geographic atrophy, agents in neovascular age-related macular degeneration, and artificial intelligence.

CGTLive sat down with experts to hear about some popular topics and discussions that took place at the 7th Annual CAR-TCR Summit 2022. Conversations included Dr. Marty Giedlin’s thoughts on the growth of automation and analytics in the cell therapy space; Dr. Christine Coughlin’s perspective on work that needs to be done to improve patient access to cell therapy; Phil Cyr’s comments on his role on a manufacturing discussion panel; Rob Richards’ experience with helping community centers gain access to cell therapies; and Dr. Sid Kerkar’s thoughts on addressing manufacturing challenges.

One of the recurring challenges in the medical cannabis space is the difficulty in conducting research because of the plant’s Schedule I status. Although there are some researchers diving in with special licenses to conduct clinical studies, there are others that are looking at real-world users to supply data. For instance, Dr. Daniel J. Kruger is a Research Investigator with the Population Study Center at the University of Michigan and Principal Investigator on a study being conducted with the Releaf app. Here, Dr. Kruger shares his interest and background in these types of surveys and his plans for the current study with Releaf on chronic pain.

Recurrent C. diff can be especially challenging for both patients and clinicians, especially as the former can have numerous bouts that can be painful and affect quality of life issues. One of the more interesting treatment areas within C diff is fecal microbiota transplants or FMTs. Although these treatments are newer they can aid clinicians and their patients and create some optimism for everyone.

In a wide-ranging video interview, Wendie Berg, MD, discussed her family history with breast cancer, the founding of www.DenseBreast-info.org, emerging research with contrast-enhanced mammography and the need for a national standard on breast density notifications.

This interview, with Carina Dolan, PharmD, Editor in Chief of Pharmacy Market Outlook, discusses the latest Pharmacy Market Outlook report that was released, and it highlights the big picture moving forward for pharmacists in hospitals and health systems.

The lack of hospital price transparency tools has been a longstanding issue limiting the uptake of value-based care services for beneficiaries and employers seeking to reduce financial waste. On this week’s Behind the Science, employer coalition leaders from across the United States spoke with The American Journal of Managed Care® on the issue of hospital price gouging in their respective markets, price negotiation strategies for employers in engaging with providers and health plans, and current and future legislative action to address these concerns.

Doug Long, vice president of industry relations at IQVIA, discussed the specialty and traditional categories in pharmaceutical spending and the parsing of them into smaller subcategories.

With ongoing gaps in mammography screening and patient anxiety that often accompanies screening exams and a possible diagnosis of breast cancer, patient education is critical. Accordingly, in a recent video interview, Amy K. Patel, MD, discussed the potential impact of new patient-oriented breast cancer screening guidelines from the National Comprehensive Cancer Network.

Stephen Greene, MD, provides a snapshot of trends in characteristics and outcomes among people with heart failure with preserved ejection fraction in the US by taking a Deep Dive into work he presented at the European Society of Cardiology Congress 2022.

There has been a great push to destigmatize conditions like depression and anxiety in recent years. And while great progress has been made in this regard, stigma remains for other psychiatric conditions, like bipolar disorder, schizophrenia, and borderline personality disorder. During the 2022 Annual Psychiatric Times™ World CME Conference in San Diego from August 11-13, several doctors spoke on this topic. Dr. Culpepper spoke about bipolar disorder and borderline personality disorder, Dr. Schneck spoke about psychiatry in general, Dr. Clayton spoke about postpartum depression, and Dr. Rao spoke about schizophrenia.

COVID-19 has extended its tentacles to all things in the medical field including how clinical trials are performed. This can be seen in how the COVID-19 vaccine trials moved these towards decentralization. Listen in how the move towards decentralization has benefits for industry and patients alike. Also, Dr. Owen Garrick, Chief Medical Officer of CVS Health Clinical Trial Services, offers some insights to achieving greater diversity overall in studies.

Recently, US News and World Report released its annual rankings on “Best Hospitals for Cancer,” in which 913 hospitals are evaluated and the top 50 ranked. Among the top centers were the Hospitals of the University of Pennsylvania and the Siteman Cancer Center at Barnes-Jewish Hospital. Following the report, CancerNetwork® editors sat down with Robert H. Vonderheide, MD, DPhil, director of the Abramson Cancer Center at the University of Pennsylvania in Philadelphia, and Timothy Eberlein, MD, director of the Alvin J. Siteman Cancer Center in Saint Louis, Missouri, about what this honor means to them and what makes their centers stand out from the rest.

Gregg Slyvester, MD, MPH, chief health officer at CSL Seqirus, discusses an FDA-approved cell-based flu vaccine for children as young as 6 months, trends in childhood vaccination rates, and how to prepare for the upcoming flu season.

The rising mental health crisis in the United States has shown staggering increases in rates of mood disorders and substance abuse, particularly among youth. On today’s Deep Dive, Jeff Temple, PhD, professor, licensed psychologist, and vice dean for research at University of Texas Medical Branch School of Nursing, discusses external triggers along with the COVID-19 pandemic that have exacerbated adverse behavioral health outcomes in adolescents and strategies for community stakeholders seeking to mitigate this crisis.

This year, the South Beach Symposium Dermatology Conference celebrated its 20th anniversary. Dr. Christopher Bunick, a member of the Editorial Advisory Board of Dermatology Times, offers his takeaways on what made this conference so great, including cadaver workshops and the latest in genomics. Here’s what he had to say.

Ambassador Deborah Birx, MD, is a world-renowned medical expert and leader whose long career has focused on clinical and basic immunology, infectious disease, pandemic preparedness, vaccine research, and global health. Birx served the United States as an Army Colonel and later, running some of the most high-profile and influential programs at the U.S. Centers for Disease Control and Prevention and U.S. Department of State.

CancerNetwork’s Audrey Sternberg spoke with Kirsten West, a naturopathic doctor who specializes in integrative oncology and recently joined the Riordan Clinic based in Wichita, Kansas. Dr. West has a Fellowship with the Oncology Association of Naturopathic Physicians and holds a Metabolic Approach to Cancer certificate from the Metabolic Terrain Institute of Health. In the interview, West dives into the field of integrative oncology by explaining its importance to the overall cancer care paradigm. She details recent advances in the field and spotlights how she and her colleagues play an important role in the multidisciplinary oncology team.